Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

  1. Tools & Tips
  2. Nicotine Replacement Therapy: Nicotine Lozenge

Nicotine Replacement Therapy: Nicotine Lozenge

DOSAGE 2mg, 4mg

What Does This Medication Do?

Use the nicotine lozenge as needed to manage breakthrough cravings and urges to use tobacco.

How Do I Use It?

  • Begin using the lozenge on your quit date.
  • Let the lozenge dissolve in your mouth near your cheek and gum.
  • Rotate the lozenge to different parts of the mouth. One lozenge lasts 20–30 minutes. A mini lozenge lasts 10–15 minutes.
  • Do not chew or swallow the lozenge.
  • Avoid eating or drinking anything acidic 15 minutes before using the lozenge or during use.
  • You may start with up to 20 lozenges per day and then reduce over time.

What Are The Possible Side Effects?

  • May cause indigestion, upset stomach, nausea, hiccups, headache, mouth irritation and difficulty sleeping. Proper lozenge use can help to avoid these side effects.
  • If you have any intolerable side effects, stop using the lozenge and contact your healthcare provider.

If you are in crisis, call: 988 or 1-800-273-TALK and press 1 to talk to someone now.

Use These Tools For Additional Support

If you use tobacco occasionally while taking the medicine, don’t give up. Continue to take the medicine and try not to use tobacco. 

Sign Up For SmokefreeVET Text

Call the Quitline to Speak with a Quit VET coach Monday - Friday 

Using medication together with behavioral counseling gives you the best chance of stopping tobacco use. Talk with your health care provider about the best medication for you.

What NRT Can You Combine?

Nicotine Patch and Lozenge

The patch and lozenge release nicotine throughout the day to help decrease withdrawal symptoms and control cravings while you quit tobacco.

Nicotine Patch, Lozenge, and Counseling

The patch and lozenge release nicotine to help decrease withdrawal symptoms and control cravings. Use with counseling for your best chance of quitting tobacco.